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The Paradox of the Organism

Adaptation and Internal Conflict
Brief Description
Leading evolutionary theorists and philosophers come together to understand how organisms persist, even as they are riddled with internal conflict, from cancer cells to selfish genes. How does a vast menagerie of organs, tissues, cells, and genes coalesce to form a unified organism? For centuries, biologists... Read More
Format: Hardback
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The Paradox of the Organism

The unity of the organismβ€”an assembly of organs, tissues, cells, and genes working toward a common goalβ€”has long been taken for granted. The essays in this collection pierce the organismal veil to consider how an organism persists, even as internal conflict, from cancer cells to selfish genes, threatens its integrity and survival.

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Leading evolutionary theorists and philosophers come together to understand how organisms persist, even as they are riddled with internal conflict, from cancer cells to selfish genes.

How does a vast menagerie of organs, tissues, cells, and genes coalesce to form a unified organism? For centuries, biologists and philosophers have taken this astonishing feat for granted, treating it as a matter of divine will or evolutionary inevitability. Yet unity is hardly assured. From cancer cells to selfish genes, the body is riven by internal conflicts.

The Paradox of the Organism grapples with this puzzle. As the essays in this collection show, profound questions arise when we pierce the organismal veil and consider the self-replicating elements within. Is an organism really a cohesive agent that adapts to the ecosystem it inhabits? Or is an organism itself an ecosystem, within which individual components are engaged in a continuous arms race?

The answers have immediate implications: for understanding miscarriage, treating cancer, improving psychological health, and preserving biodiversity. Challenging fundamental precepts of evolutionary theory, The Paradox of the Organism offers an incisive account of life's extraordinary success.

Book Details

INFORMATION

ISBN: 9780674296381

Publisher: Harvard University Press

Format: Hardback

Date Published: 16 December 2025

Country: United States

Imprint: Harvard University Press

Illustration: 18 illus., 3 tables

Contributors:

  • Edited by J. Arvid Γ…gren
  • Edited by Manus M. Patten

Audience: Professional and scholarly

DIMENSIONS

Width: 156.0mm

Height: 235.0mm

Weight: 0g

Pages: 336

About the Author

J. Arvid Γ…gren is Research Associate at the Lerner Research Institute of the Cleveland Clinic and Affiliated Researcher at the Evolutionary Biology Centre at Uppsala University. He is the author of The Gene’s-Eye View of Evolution. Manus M. Patten is an evolutionary biologist whose research explores the consequences of conflict, both for organisms and for evolutionary theory. He is Teaching Professor in Biology at Georgetown University.

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