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Genome Editing in Drug Discovery
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Genome Editing in Drug Discovery
$40299
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Unavailable
Book Hero Magic created this recommendation. While it's new and still learning, it may not be perfect - your feedback is welcome! IS THIS YOUR NEXT READ?
Book Hero Magic formatted this description to make it easier to read. While it's new and
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Description
Genome Editing in Drug Discovery
A practical guide for researchers and professionals applying genome editing techniques to drug discovery.
In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology’s history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues.
The safety and efficacy of drugs and new target discovery, as well as next-generation therapeutics are also presented.
Offering practical suggestions for practitioners and academicians involved in drug discovery, Genome Editing in Drug Discovery is a fulsome treatment of a technology that has become part of nearly every early step in the drug discovery pipeline. Selected contributions also include:
- A thorough introduction to the applications of CRISPRi and CRISPRa in drug discovery
- Comprehensive explorations of genome-editing applications in stem cell engineering and regenerative medicine
- Practical discussions of the safety aspects of genome editing with respect to immunogenicity and the specificity of CRISPR-Cas9 gene editing
- In-depth examinations of critical socio-economic and bioethical challenges in the CRISPR-Cas9 patent landscape
Perfect for academic researchers and professionals in the biotech and pharmaceutical industries, Genome Editing in Drug Discovery will also earn a place in the libraries of medicinal chemists, biochemists, and molecular biologists.
Book Details
INFORMATION
ISBN: 9781119671343
Publisher: John Wiley & Sons Inc
Format: Hardback
Date Published: 01 April 2022
Country: United States
Imprint: John Wiley & Sons Inc
Contributors:
- Edited by Marcello Maresca
- Edited by Sumit Deswal
Audience: Professional and scholarly
DIMENSIONS
Spine width: 21.0mm
Width: 216.0mm
Height: 279.0mm
Weight: 1107g
Pages: 352
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About the Author
Marcello Maresca, PhD, is a Senior Director in the Discovery Sciences Department at AstraZeneca. He obtained his doctorate in Molecular Biology from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany.
Sumit Deswal, PhD, is an Associate Principal Scientist with the Genome Engineering Team at AstraZeneca R&D in Sweden. He obtained his doctorate in Immunology from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany.
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