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Dynamics and Kinetics in Structural Biology

Unravelling Function Through Time-Resolved Structural Analysis
By Keith Moffat and Eaton E. Lattman
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Book Hero Magic crafted this summary to help describe this book. While it's new and still learning, it may not be perfect - your feedback is welcome! Summary
Dynamics and Kinetics in Structural Biology by Keith Moffat and Eaton E. Lattman offers an exploration of the fundamental principles underlying the movements and interactions within biological macromolecules. The book delves into essential topics such as the mechanisms that drive molecular conformational changes and the methods used to analyse these dynamics. Aimed at those with an interest in the molecular biology and biophysics fields, it bridges theoretical and practical aspects to enhance understanding of biological processes at the molecular level.
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Format: Hardback
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Book Hero Magic created this recommendation. While it's new and still learning, it may not be perfect - your feedback is welcome! IS THIS YOUR NEXT READ?

This book may appeal to you if you are fascinated by the intricate movements and interactions within biological macromolecules, offering insights into their dynamic behaviour at the atomic level. With a focus on structural biology, it provides a comprehensive understanding of how these structures function and transform, which could be intriguing for those captivated by the complexity of life at a molecular scale. Science enthusiasts with a keen interest in molecular biology and biophysics might find this exploration particularly enlightening.

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Book Hero Magic formatted this description to make it easier to read. While it's new and still learning, it may not be perfect - your feedback is welcome! Description

Dynamics and Kinetics in Structural Biology

Understand the latest experimental tools in structural biology with this pioneering work.

Structural biology seeks to understand the chemical mechanisms and functions of biological molecules, such as proteins, based on their atomic structures. Until recently, these structures have been studied only statically, using procedures which deliberately freeze atomic motion. However, freezing eliminates the rapid structural motions so essential to biological activity and function; the molecules are inactive. But with the recent development of X-ray free electron laser (XFEL) sources, efforts to conduct dynamic experiments have expanded using the principles of dynamics and kinetics to capture active biological molecules as they function.

Dynamics and Kinetics in Structural Biology promotes the development of these experiments and their successful application. It grounds readers in the foundational principles of dynamics and kinetics, proceeds through extended discussions of experimental procedures and data analysis techniques, and explores experimental frontiers in structural dynamics. The book will aid researchers to gather and interpret cutting-edge data on the dynamic structure of biological molecules, under conditions where they retain their biological functions.

Dynamics and Kinetics in Structural Biology offers readers:

  • Authorship by founding figures in the field
  • In-depth presentation of time-resolved X-ray crystallography, solution scattering, and more
  • A pioneering contribution to a rapidly developing field of study

Dynamics and Kinetics in Structural Biology is essential reading for graduate students, scientists, researchers, and industry professionals engaged in structural studies of biological systems. Industry professionals considering dynamic studies in the development of new product lines will also benefit.

Book Details

INFORMATION

ISBN: 9781119696285

Publisher: John Wiley & Sons Inc

Format: Hardback

Date Published: 01 December 2023

Country: United States

Imprint: John Wiley & Sons Inc

Audience: Professional and scholarly

DIMENSIONS

Spine width: 21.0mm

Width: 170.0mm

Height: 244.0mm

Weight: 709g

Pages: 288

Collections

Eaton E. Lattman Education & Reference Keith Moffat Non-Fiction Science & Nature

About the Author

Keith Moffat, PhD is the Louis Block Distinguished Service Professor of Biochemistry and Molecular Biology and a founding member of the Institute for Biophysical Dynamics, University of Chicago, USA. He pioneered the technique of time-resolved crystallography and has published very widely in the fields of biophysics and biochemistry.

Eaton E. Lattman, PhD has served as Professor at the Johns Hopkins University and the University at Buffalo, among other roles. He was director of BioXFEL, an NSF-sponsored center for the application of X-ray lasers to biology. He has years of experience in the fields of X-ray crystallography, structural biology, and related areas.

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