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How We Age
The Science of Longevity
Brief Description
How recent breakthroughs in longevity research offer clues about human aging All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer...
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How We Age
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Description
How recent breakthroughs in longevity research offer clues about human aging
All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.
Understanding the fundamental biological rules that govern aging in model systems provides clues about how we might slow human aging, which could lead in turn to new therapeutics and treatments for age-related disease.
Among other vivid examples, Murphy describes research that shows how changing a single gene in the nematode worm C. elegans doubles its lifespan, extending not only the end of life but also the youthful, healthy part of life. Drawing on work in her own lab as well as other recent research, Murphy chronicles the history and current state of the field, explaining longevity's links to reproduction and mating, sensory and cognitive function, inheritances from our ancestors, and the gut microbiome.
Written with clarity and wit, How We Age provides a guide to the science: what we know about aging, how we know what we know, and what we can do with this new knowledge.
Book Details
INFORMATION
ISBN: 9780691256825
Publisher: Princeton University Press
Format: Paperback / softback
Date Published: 20 May 2025
Country: United States
Imprint: Princeton University Press
Illustration: 7 b/w illus.
Audience: General / adult
DIMENSIONS
Width: 133.0mm
Height: 203.0mm
Weight: 250g
Pages: 464
About the Author
Coleen T. Murphy is director of the Lewis Sigler Institute of Genomics and professor of genomics and molecular biology at Princeton University. She is also director of Princeton's Glenn Foundation for Research on Aging and the director of the Simons Collaboration on Plasticity in the Aging Brain.
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