Biomaterials and Immune Response

The interactions of biomaterials with the host immune system are crucial for their functionality. Biomaterials and Immune Response aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications.

To this end, the book has dedicated chapters for:

i) Explaining immune cells taking part in the immune response to the biomaterials/immune systems interface.

ii) The effect of biomaterial shape, form, and physicochemical properties on the response of the immune system.

iii) Biofilm formation on implanted materials as a failure of immune system/biomaterial interactions.

iv) Tissue-specific effects of the immune response and its consequences for tissue engineering and regenerative medicine.

v) Immune reaction in a clinical context (periodontology).

In the field of biomaterials, there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For a better understanding of such techniques, it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve clinical outcomes by developing immune-instructive biomaterials.

• Provides keen insight into biomaterial–immune cell interactions.
• Presents an explanation of state-of-the-art methodologies in immunomodulation.
• Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions, suitable for materials scientists engaged with a biology-intensive topic.
• Explores a comprehensive overview of biomaterial-related complications.
• Provides extensive references at the end of each chapter to enhance study in this highly active research area.