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Medicinal Chemistry

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Medicinal Chemistry offers a comprehensive introduction to the field with a focus on practical application. Authored by experienced medicinal chemists, it combines foundational principles of synthetic organic chemistry and structural biology with real-world drug discovery techniques. The textbook includes case studies, historical context, detailed assays, and exercises designed for advanced undergraduates, graduate students, and professionals entering the drug discovery sector.
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Format: Paperback / softback
$25900
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Book Hero Magic created this recommendation. While it's new and still learning, it may not be perfect - your feedback is welcome! IS THIS YOUR NEXT READ?

Ideal for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry, as well as pre-medical, pre-pharmacy students and professionals seeking a practical reference in drug discovery.

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Medicinal Chemistry teaches the essential concepts of medicinal chemistry from the perspective of practicing.

Book Hero Magic formatted this description to make it easier to read. While it's new and still learning, it may not be perfect - your feedback is welcome! Description

Medicinal Chemistry teaches essential concepts by focusing on how the field is actually practised, melding real-world research experience with basic principles and modern methods. Written by practising medicinal chemists, this textbook is intended for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry. Pre-medical or pre-pharmacy students and professionals entering the drug discovery field will also find it a useful reference.

Building on a foundation of synthetic organic chemistry and structural biology, the book interweaves therapeutics, case studies, historical context, and techniques for discovering, developing, and optimising new drugs. Chapters are richly illustrated and include problems and annotated journal references with accompanying exercises and answers.

  • Authored by practising medicinal chemistsβ€”melding real-world research experience with basic concepts and up-to-date methods.
  • Flexible in presentationβ€”the first five chapters provide a conceptual foundation and historical understanding of the field; subsequent chapters explore the application of concepts. Chapters can be assigned in order of instructor preference and desired emphasis.
  • Presents easy-to-follow tables and descriptions of assays next to their relevance to medicinal chemistry and drug discovery, along with target valuesβ€”information rarely found all in one place, but is a crucial reference.
  • Case studies and Journal Club use current literature to apply concepts from the text to real-life examples. They are also suitable for flipped classrooms and self-study.

Book Details

INFORMATION

ISBN: 9780815345565

Publisher: Taylor & Francis Inc

Format: Paperback / softback

Date Published: 17 April 2018

Country: United States

Imprint: CRC Press Inc

Illustration: 588 Illustrations, color

Audience: General / adult, Tertiary education, Professional and scholarly

DIMENSIONS

Width: 210.0mm

Height: 212.0mm

Weight: 1170g

Pages: 508

About the Author

Norma Dunlap is Professor of Chemistry at Middle Tennessee State University, where she specializes in synthetic organic chemistry and medicinal chemistry. Her research interests include the design and synthesis of bioactive compounds, as well as isolation, identification, and synthesis of bioactive natural products. She holds a PhD in Organic Chemistry from the University of Wyoming and was an NIH Postdoctoral Fellow at the University of Pennsylvania. Prior to an academic career, she was a Senior Research Scientist in drug discovery at Hoffmann-LaRoche.Donna M. Huryn is Research Professor in the Department of Pharmaceutical Sciences at the University of Pittsburgh and Adjunct Professor of Chemistry at the University of Pennsylvania and. Her research focuses on identi_cation, characterization, and optimization of small molecule probes and drugs to treat cancer, neurodegeneration and infectious diseases. She holds a PhD from the University of Pennsylvania and started her career as a medicinal chemist in the pharmaceutical industry. She is the Principal Investigator of the University of Pittsburgh Chemical Diversity Center and is a Fellow of the American Chemical Society.

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