{"product_id":"drug-metabolism-and-pharmacokinetics-by-liang-shen-9781394300129","title":"Drug Metabolism and Pharmacokinetics","description":"\u003cdiv class=\"book-description\"\u003e\n\u003cp\u003e\u003cstrong\u003ePractical, state-of-the-art pharmacokinetic research methods, ideas, advancements, applications, and strategies\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eDrawing on a wealth of extensive practical experience and theoretical research, \u003cem\u003eDrug Metabolism and Pharmacokinetics\u003c\/em\u003e encapsulates the most recent advancements and illustrative applications in the field. Sixty-eight relatively independent yet interconnected articles are included, each offering a unique perspective and providing in-depth interpretation. Readers can either read systematically or select specific topics of interest from the table of contents.\u003c\/p\u003e\n\n\u003cp\u003eBasic concepts, frontier advancements, DMPK research strategies, and technical methods are covered for novel drug modalities and therapeutics in different disease areas. The book encompasses a wide range of application and validation cases for DMPK research, including studies in \u003cem\u003ein vitro\u003c\/em\u003e ADME, \u003cem\u003ein vivo\u003c\/em\u003e pharmacokinetics, metabolite profiling and identification, radiolabeled ADME, and bioanalysis. Case studies showing the application of topics covered are included throughout, along with valuable insights into problem-solving and critical thinking.\u003c\/p\u003e\n\n\u003cp\u003eWritten by a team of scientists specializing in DMPK research from the DMPK Department of WuXi AppTec, \u003cem\u003eDrug Metabolism and Pharmacokinetics\u003c\/em\u003e discusses sample topics including:\u003c\/p\u003e\n\n\u003cul\u003e\n    \u003cli\u003eADME properties, metabolite identification, and bioanalytical strategies for oligonucleotide drugs\u003c\/li\u003e\n    \u003cli\u003eStrategies and challenges in the determination of drug-to-antibody ratio (DAR) values of antibody-drug conjugates (ADCs)\u003c\/li\u003e\n    \u003cli\u003eBreaking barriers in CNS drug development with intrathecal and intracerebroventricular administration\u003c\/li\u003e\n    \u003cli\u003eApplication and detection techniques of biomarkers in drug development\u003c\/li\u003e\n    \u003cli\u003eFlux dialysis method for assessing plasma protein binding of high protein-binding drugs\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eDrug Metabolism and Pharmacokinetics\u003c\/em\u003e is an essential forward-thinking reference on the subject for pharmacy students, pharmaceutical industry researchers, and DMPK scientists, especially those exploring novel drug modalities.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Unknown","offers":[{"title":"Default Title","offer_id":47430649053420,"sku":"9781394300129","price":543.99,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0705\/7784\/8556\/files\/9781394300129.jpg?v=1774558918","url":"https:\/\/bookhero.co.nz\/products\/drug-metabolism-and-pharmacokinetics-by-liang-shen-9781394300129","provider":"Book Hero","version":"1.0","type":"link"}